Hyperinsulinemia predisposes to NAFLD
نویسندگان
چکیده
منابع مشابه
Maternal hyperinsulinemia predisposes rat fetuses for hyperinsulinemia, and adult-onset obesity and maternal mild food restriction reverses this phenotype.
We have previously shown that artificial rearing of newborn female rat pups on a high-carbohydrate (HC) milk formula resulted in chronic hyperinsulinemia and adult-onset obesity (HC phenotype) and that the maternal HC phenotype was transmitted to their progeny (2-HC rats) because of fetal development in the HC female rat. The aims of this study were to investigate 1) the fetal adaptations that ...
متن کاملVasodilator response to local hyperinsulinemia.
Vasodilator Response to Local Hyperinsulinemia To the Editor: Cardillo et al recently reported that systemic but not local hyperinsulinemia causes nitric oxide (NO)-dependent vasodilatation.1 They suggest that mechanisms stimulated only by systemic but not local hyperinsulinemia contribute to insulinmediated vasodilatation. We believe that this conclusion is mistaken. The changes in forearm blo...
متن کاملAdrenomedullin Haploinsufficiency Predisposes to Secondary Lymphedema
Secondary lymphedema is a debilitating condition, and genetic factors predisposing to its development remain largely unknown. Adrenomedullin (AM) is peptide encoded, together with proadrenomedullin N-terminal peptide (PAMP), by the Adm gene (adrenomedullin gene). AM and its putative receptor calcitonin receptor-like receptor (CLR) are implicated in angiogenesis and lymphangiogenesis during embr...
متن کاملChildhood asthma predisposes to spontaneous pneumomediastinum.
Spontaneous pneumomediastinum is a rare condition for which potentially life threatening differential diagnoses must be excluded. A case is presented of a young man with a history of severe childhood asthma, who was successfully treated conservatively.
متن کاملRestricted MHC–peptide repertoire predisposes to autoimmunity
MHC molecules associated with autoimmunity possess known structural features that limit the repertoire of peptides that they can present. Such limitation gives a selective advantage to TCRs that rely on interaction with the MHC itself, rather than with the peptide residues. At the same time, negative selection is impaired because of the lack of negatively selecting peptide ligands. The combinat...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Indian Journal of Clinical Biochemistry
سال: 2008
ISSN: 0970-1915,0974-0422
DOI: 10.1007/s12291-008-0030-6